Top 10 Cancers difficult to cure

Top 10 Cancers difficult to cure


  • Pancreatic cancer
  • Cholangiocarcinoma
  • Liver cancer
  • Gastric cancer
  • Breast cancer
  • Cervical cancer
  • Leukemia
  • Esophageal cancer
  • Lung cancer
  • Colorectal cancer

The top ten cancers that are difficult to cure, first of all pancreatic cancer, also include cholangiocarcinoma, liver cancer, gastric cancer, breast cancer and cervical cancer, and other cancers with poor prognosis.

1. Pancreatic cancer: Known as the king of cancer, some studies have found that the incidence and mortality of pancreatic cancer are close to 1:1. Due to the relatively deep position of the pancreas in the human body, it is often difficult to find pancreatic cancer in the early stage. Even if pancreatic cancer is diagnosed with clinical symptoms, the difficulty of surgery is relatively severe, and the risk of surgery is also very high. In addition, pancreatic cancer cells are often highly malignant, prone to spread and metastasis, and are less sensitive to radiotherapy and chemotherapy, and the prognosis is inferior.

2. Cholangiocarcinoma: Cholangiocarcinoma is a malignant tumor derived from bile duct epithelial cells. The etiology is not clear at present, and the effect of radiotherapy and chemotherapy is usually uncertain. The incidence of cholangiocarcinoma is relatively low, but the degree of malignancy of cholangiocarcinoma is usually relatively high, and the prognosis is relatively poor. Some metastatic cholangiocarcinomas may have lost the opportunity for surgical treatment after diagnosis. If cholangiocarcinoma has metastasized, surgical treatment is not ideal, so cholangiocarcinoma is more difficult to cure.

3. Liver cancer:  Because liver cancer itself has a strong inhibitory effect, it is less sensitive to chemotherapy and radiotherapy. In addition, many liver cancer patients will be combined with viral hepatitis and cirrhosis. Or the tolerance of radiotherapy is relatively poor, especially the prognosis of patients with short-term liver cancer is relatively poor.

4. Gastric cancer: In the early stage, it often lacks specific gastrointestinal symptoms and is easily confused with benign gastric ulcer or chronic gastritis. Early gastric cancer can be treated with surgery, while advanced gastric cancer is often more malignant and less sensitive to chemotherapy, and the treatment method is relatively simple.

5. Breast cancer: The epithelial cells of the breast may become malignant, which can lead to the development of breast cancer. The tumor cells first form a mass in the breast and grow, gradually invading the surrounding normal tissues, causing the breast to harden and the skin to ulcerate and rot. And metastasize to distant organs, causing body dysfunction. The mortality rate of breast globally is very high. At present, the pathogenesis is not very clear. If breast cancer spreads to other fatal organs, it will usually lead to death soon. Cancers are considered more challenging to treat.

6. Cervical cancer: Cervical cancer is women’s second most common tumor. It usually has no symptoms within 5-10 years, so once it is discovered, it may have reached an advanced stage and is difficult to cure. However, if you have regular physical examinations and early detection, The success rate of cure is still very high.

7. Leukemia: Leukemia is a malignant tumor that occurs in the hematopoietic system. It is characterized by the unlimited proliferation of white blood cells in body tissues, infiltrating all body organs, immature white blood cells appearing in the blood circulation, and often accompanied by increased white blood cells. The main clinical symptoms are fever, anemia, bleeding, and enlargement of the liver, spleen, and lymph nodes in different degrees. Due to the decrease of white blood cells and low immunity of leukemia patients, it is usually difficult to cure.

8. Esophageal cancer: Esophageal cancer will affect eating and vocalization and even affect the trachea and lungs, leading to symptoms of dyspnea. If the situation is difficult, it will cause more significant damage to the liver and brain. It usually occurs in multiple and multi-point locations, and it is difficult to be cured by surgery or radiation therapy.

9. Lung cancer: Lung cancer usually has a relatively high degree of malignancy and is very prone to progression and metastasis. Although most small cell lung cancers have a relatively high response rate when they are first treated, most patients will quickly relapse.

10. Colorectal cancer: Colorectal cancer is a common disease threatening human health. Usually, the early symptoms are not obvious. It can spread to other tissues through lymphatic blood circulation and direct spread, causing symptoms such as anemia and weight loss. It is more difficult to cure.

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Dr AF Saeed

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