Mathematical mechanistic model representing the cancer immunity cycle under radiation effects



Summary

This content focuses on a mathematical model designed to simulate the intricate interplay between cancer cells and the immune system, specifically considering the impact of radiation therapy. This “mechanistic model” aims to capture the key steps of the cancer-immunity cycle, such as antigen presentation, T-cell activation, and tumor cell killing. By incorporating the effects of radiation, the model can predict how radiation alters these interactions, potentially leading to enhanced or suppressed immune responses. Ultimately, this model serves as a tool to understand and optimize radiation therapy strategies to improve anti-tumor immunity.

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