Antigen Presenting Cells Antigen-presenting cells (APCs) play a crucial role in the immune system, bridging innate and adaptive immunity. They are responsible for capturing, processing, and presenting antigens to T cells, thus enabling the body Read More
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Intracellular Events in Antigen Processing Antigen processing is a vital step in the immune system’s ability to recognize and respond to pathogens. It involves the breakdown of proteins into smaller peptides that can interact Read More
Antigen cross-presentation Antigen cross-presentation is a critical immunological process that allows exogenous antigens, typically presented via MHC class II to CD4+ T cells, to be presented on MHC class I molecules for recognition by CD8+ Read More
MHC Assembly and Trafficking The Major Histocompatibility Complex (MHC) is a critical component of the immune system, essential for the recognition of foreign molecules and the subsequent immune response. MHC molecules are categorized into two Read More
Topics in Immunology Topic Categories ANTIGEN PROCESSING AND PRESENTATION BASIC AUTOIMMUNITY CELLULAR ADHESION, MIGRATION, AND INFLAMMATION CYTOKINES AND CHEMOKINES AND THEIR RECEPTORS HEMATOPOIESIS AND IMMUNE SYSTEM DEVELOPMENT IMMEDIATE HYPERSENSITIVITY, ASTHMA, AND ALLERGIC RESPONSES IMMUNE MECHANISMS Read More
Major Histocompatibility Complex (MHC) Structure, Function & Ligands Contents Introduction There is no biological system more important than the immune system. Its primary function is to shield the organism from potential dangers. Growing up in Read More
ELISA Immunoassay Detailed Protocol Enzyme-linked immunosorbent Assay (ELISA) is a biochemical method used to detect the presence and concentration of antibodies or antigens in a sample. Materials needed: – ELISA Plates – Target antigen or antibody – Non-reactive Read More
Protocol for Mouse spleen isolation and preparation of single-cell suspension Before carrying out any lab procedures, please consult your lab protocol and safety guidelines. Also, ensure all equipment used has been cleaned and sterilized according Read More
TCR Sequencing Protocol T-cell receptor (TCR) sequencing is a technique used to analyze or profile the repertoire of T-cell receptor sequences in a sample. This advanced immunogenetics method provides important insights about immune responses and Read More