Antigen-specific Treg cells induce infectious tolerance Summary Antigen-specific regulatory T cells (Tregs) can induce “infectious tolerance,” a powerful mechanism where Tregs not only suppress immune responses against a specific antigen but also convert other immune Read More
Tags :Tolerance
Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles
Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles to establish T-cell tolerance Summary Engineering allogeneic CAR-T cells that retain their T cell receptor (TCR) could overcome challenges of current CAR-T therapies. By understanding Read More
Science, Volume 389, Issue 6761, Page 684-685, August 2025. Summary Without knowing the specific content of those pages, a summary is impossible. However, I can offer a general statement: Science, Volume 389, Issue 6761, pages 684-685, published in August 2025, likely Read More
Cooperative role of MDSCs and Tregs in alum-induced alloimmune tolerance
Cooperative role of MDSCs and Tregs in alum-induced alloimmune tolerance in corneal transplantation Summary Alum, a common vaccine adjuvant, can induce alloimmune tolerance in corneal transplantation by fostering a collaborative relationship between myeloid-derived suppressor cells (Read More
Science, Volume 389, Issue 6757, Page 236-237, July 2025. Summary Without knowing the specific content of the specified issue of Science, I can only provide a general summary. Science is a leading peer-reviewed journal that publishes significant original Read More
Tolerance and Autoimmunity Tolerance and autoimmunity are foundational concepts in immunology that describe how the immune system distinguishes between the body’s own cells and foreign invaders like pathogens. Properly functioning immune tolerance prevents the Read More