TRPV1 inhibition sensitizes tumors to PD-1 blockade by reversing resistance to CTL-mediated killing Summary TRPV1 inhibition can enhance the effectiveness of PD-1 blockade immunotherapy in treating tumors. Tumors can develop resistance to cytotoxic T lymphocyte (Read More
Caffeine enhances antitumor T-cell activity by suppressing kynurenine pathway in colorectal cancer Summary A new study reveals that caffeine boosts the immune system’s ability to fight colorectal cancer by targeting the kynurenine pathway. Caffeine Read More
Rechallenge with immune-checkpoint inhibitors in patients with advanced-stage lung cancer Summary Rechallenge with immune checkpoint inhibitors (ICIs) in advanced lung cancer patients who initially benefited but later progressed is a growing area of interest. Studies Read More
Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune response Summary Pressure-fused biomineral tablets offer a promising approach for sustained interleukin-2 (IL-2) release, enhancing antitumor immune responses. This method involves compressing biominerals into tablets Read More
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