Researchers have discovered and functionally characterized the myokine CLCF1, which declines with age but is released during exercise and helps protect against musculoskeletal aging. Everyone knows that “exercise is good for your health,” but not many can actually explain why that’s the case. A joint research team led by Dr. Yong Ryoul Yang of the […]



Summary

Researchers have identified a myokine, CLCF1, released during exercise that combats musculoskeletal aging. This myokine decreases with age, but its release during physical activity offers protection. The team, led by Dr. Yong Ryoul Yang, discovered CLCF1’s age-related decline and its activation by exercise. By functionally characterizing CLCF1, they provide a deeper understanding of how exercise benefits musculoskeletal health, moving beyond the general “exercise is good” statement. This research offers insights into the molecular mechanisms behind the anti-aging effects of exercise on muscles and bones.

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