Investigating the correlation between IDO1/PD-L1 expression or co-expression and EGFR/KRAS gene mutations in advanced NSCLC



Summary

This study explores the relationship between IDO1 and PD-L1 expression (both individually and together) and the presence of EGFR and KRAS gene mutations in advanced non-small cell lung cancer (NSCLC). Researchers likely analyze tumor samples to determine if the expression levels of these immune checkpoint proteins correlate with the specific mutation status of EGFR and KRAS, which are key driver genes in NSCLC. Understanding this correlation could help predict treatment response, guide personalized immunotherapy strategies, and improve patient outcomes in advanced NSCLC based on specific genomic and immunologic profiles.

Read more…

Credits: Source

This post is part of “Science/Immunology News”, Follow for more…!!!