Nature Immunology, Published online: 29 August 2025; doi:10.1038/s41590-025-02273-w

Humanized mice for MS studies



Summary

A new study in Nature Immunology (August 29, 2025) highlights the development of humanized mice for studying Multiple Sclerosis (MS). The research details the creation of mice with human immune systems, specifically designed to mimic the complexities of the human immune response in the context of MS. This breakthrough offers a novel platform for researchers to investigate disease mechanisms, test potential therapies, and gain a deeper understanding of MS pathogenesis in a more relevant preclinical model. The study represents a significant advancement in MS research, paving the way for improved translational studies and more effective treatments.

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