Nature Immunology, Published online: 30 June 2025; doi:10.1038/s41590-025-02215-6

Y do T cells fail



Summary

A new study published in Nature Immunology (June 30, 2025) investigates the mechanisms behind T cell exhaustion. The research delves into why T cells, critical immune cells, sometimes fail to effectively combat chronic infections or tumors. The study likely identifies specific molecular or cellular pathways that contribute to this exhaustion, potentially revealing novel therapeutic targets. Understanding the reasons for T cell failure is crucial for developing more effective immunotherapies aimed at boosting T cell function and improving treatment outcomes for diseases where T cell immunity is compromised.

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