Mouse olfactory organoids revealed stem cells that preserve smell, offering clues to treat age- and disease-related smell loss.



Summary

Mouse olfactory organoids, miniature 3D models of the nasal cavity’s smell-detecting tissue, have revealed the presence of resident stem cells crucial for maintaining olfactory function. These stem cells can differentiate into various cell types responsible for the sense of smell, offering a potential pathway to regenerate damaged olfactory neurons. This discovery holds significant promise for developing new therapies to combat age-related and disease-related smell loss, conditions that severely impact quality of life. By understanding and harnessing the regenerative power of these stem cells, researchers aim to restore olfactory function in individuals suffering from impaired smell.

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