Are you passionate about understanding how neural circuits generate behavior?

The Stagkourakis Lab at Karolinska Institutet (KI) and SciLifeLab in Stockholm is recruiting for a postdoctoral researcher in experimental systems neuroscience.  

Our research combines in vivo large-scale electrophysiology (Neuropixels), AAV-based circuit targeting, behavior, and imaging approaches such as miniscope and two-photon microscopy. We maintain a strong commitment to technical innovation and behavioral rigor.

We are looking for a highly motivated and independent individual with a passion for science. Requirements for the position include a doctoral degree in areas relevant to the project, such as tissue damage signaling and repair, immunity, metabolism, and stem cell biology. Hands-on experience working with bioinformatics analysis, especially RNAseq, is required, while experience in ATACseq and scRNAseq is considered advantageous. In addition, hands-on experience in working with zebrafish as an experimental model, including embryonic, juvenile, and adult life stages, microscopy (brightfield/fluorescence and confocal), and FACS-based cell sorting, is considered highly advantageous.

The candidate must be able to work within a team of scientists from different disciplines and nationalities, and fluency in English, both written and oral, is a requirement. As the position also entails teaching and student supervision, documented experience in in teaching/supervision is considered advantageous.

To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled no later than the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

We are seeking one Postdoc with PhD and laboratory research experience with focus on viral immunology, who will work as an integrated researcher in our team while maintaining significant research independence, being involved in several ongoing projects.

You will be a member of the experimental research group of  Senior Professor Anders Sönnerborg at the Centrum for Infectious Medicine (CIM), subunit Clinical Infectious Diseases (CID), Department of Medicine, Huddinge, which is nationally and internationally competitive center for infectious diseases research. The research group conducts innovative studies on the interaction between the immune system and chronic viral infections; HIV, HSV, HBV, with special emphasis on HIV. The studies are translational in nature and involve the usage of cutting-edge bulk- and single cell technologies, including high-parameter flow cytometry, gene-expression, RNA-seq, proteomics analysis and HIV isolation/cultivation in BSL3 labs to dissect the interaction between the immune system and HIV as well as the development and characterization of new antivirals. Through these platforms, we study different aspects of the interaction between HIV, antivirals and the immune system.

We are seeking a highly motivated bioinformatician with a strong background in multi-omics data analysis to join our research team focused on cancer biology. This role offers the opportunity to contribute to cutting-edge investigations into tumor genomics, transcriptomics, and proteomics, with the goal of uncovering novel biological insights and informing the development of next-generation cancer therapies.

The successful candidate will lead the development and maintenance of robust computational pipelines for the integration of high-throughput sequencing data, including de novo transcriptome assembly and open reading frame (ORF) prediction. A key aspect of the work involves translating transcriptomic data into custom protein databases to support mass spectrometry-based proteomics, enabling the discovery of tumor-specific antigens.

This position is ideal for a scientist who thrives in a collaborative, interdisciplinary environment and is passionate about applying computational approaches to complex biological questions. The role also includes the development of tools and resources to support the clinical translation of research findings, particularly in the context of targeted immunotherapies.

As a postdoctoral researcher, you will join our team, whose goal is to advance the knowledge of drug safety in pregnancy with large-scale data-driven surveillance using Swedish nationwide health registers.

Your primary role as a member of our team will be to design and conduct advanced statistical analyses under the guidance of the main supervisor and her collaborators. This includes developing and preregistering detailed analysis plans, writing reproducible code for data processing and statistical modeling, and interpreting results within the broader context of existing evidence.

To support this, you will also assist with manual and semi-automatic systematic literature reviews. Furthermore, you will contribute to CPE’s pharmacoepidemiological studies on drug utilization and safety, using national health registers from Sweden and conducted in collaboration with researchers from other Nordic and international research groups. You will also be expected to participate in the supervision of doctoral or master’s students, as well as activities related to research at CPE and in the Clinical Epidemiology Division (KEP).

We are seeking a highly motivated and skilled postdoctoral researcher to join our team for an exciting project investigating mitochondrial function in adipocytes. The focus of the project is a poorly characterized protein localized to adipocyte mitochondria, predicted to act as an oxidoreductase. Our preliminary findings show that loss of this protein impairs insulin-stimulated conversion of glucose into fatty acids. In addition, mass spectrometry-based tracing of glucose reveals reduced labeling of TCA cycle intermediates, suggesting a broader defect in mitochondrial glucose metabolism.

The successful candidate will dissect the molecular and metabolic functions of this protein using a combination of in vitro and in vivo approaches. This includes leveraging our existing metabolomic tracing datasets to map altered metabolic pathways and analyzing an adipocyte-specific knockout mouse model to evaluate systemic metabolic consequences. Specifically, the project will integrate cutting-edge cell biology techniques, including CRISPR/Cas9-based gene editing (e.g., CRISPRi/a, base editing), confocal microscopy, and metabolic flux analysis in human adipocytes. These in vitro studies will be complemented by comprehensive in vivo metabolic phenotyping, including metabolic cage experiments and glucose and insulin tolerance tests in knockout mice. To gain mechanistic insights, the candidate will lead transcriptomic and proteomic profiling of both human adipocytes and mouse tissues.

Your main role will be to further develop a novel risk prediction tool developed by our group and validate this in several international collaborations. The role may involve travelling to other countries when needed. Another task will be to use unique imaging data to predict incident liver disease. 

You will have the opportunity to work within an interdisciplinary as well as an international setting. At our department, you will have vast opportunities to engage and participate in various research forums, outside as well as inside the department. There will also be an opportunity to engage in teaching for the interested candidate. We are located at the Department of Medicine, Huddinge, which is an inclusive workplace, encouraging collaborative departmental and interdisciplinary research. This is a position of two years with possibility of extension.

As a postdoctoral fellow, you will lead a project aimed at uncovering how interdependencies between skills influence human social learning and contribute to collective outcomes, such as the dynamics of cultural evolution.

In this role, you will:

• Work at the forefront of research in social learning and cultural evolution, developing novel computational and experimental models to understand these phenomena.
• Have the opportunity to develop your own research ideas within the lab’s focus areas.
• (Depending on your interests) Be responsible for the development and analysis of computational and mathematical models.
• (Depending on your interests) Conduct experimental tests (in-person or online) to evaluate the assumptions and predictions of these models.
• Be responsible for the dissemination of results through publications and presentations.

You will join a successful and well-funded research group at the Karolinska Institute, collaborating with senior and junior researchers in a supportive and stimulating environment. The project involves collaboration with two other research groups: those of Lucas Molleman at the University of Amsterdam (where a PhD student is working on the same project) and Pieter van den Berg at KU Leuven. Research visits to Amsterdam and/or Leuven are possible.

The Baranello Lab – Drawing from our expertise in the fields of topoisomerase and cancer biology, we aim to answer fundamental questions about how transcription, replication and DNA topology are functionally coordinated in human cells. We use state-of-the-art approaches to assess transcriptomic, epigenomic and replisomic profiles, as well as molecular biology, advanced microscopy and drug screens to understand how topoisomerase regulation affects fundamental nuclear processes (key lab references: Baranello et al. Cell 2016; Wiegard et al. Molecular Cell 2021; Das et al. Molecular Cell 2022; Cameron et al. Science Advances 2023). The overall aim is to reveal novel cancer therapy targets and improved strategies for personalized treatment.

Recently we have identified a protein complex called “topoisome” in which the oncoprotein MYC recruits and increases the catalytic activities of both Topoisomerase 1 and 2 to promote high rates of transcriptional (Das et al. Molecular Cell 2022). The successful candidate will play a leading role in a full-time research project funded by the European Research Council Consolidator Grant, focused to address the functional role of the topoisome during transcription. Specifically we want to study the coordination of the topoisome and the transcriptional machinery. The outcome of this work is predicted to inspire a new strategy to target MYC in cancer, which will be tested in MYC-driven cancer models. This multidisciplinary project involves master biochemistry, master molecular biology, proteomics/genomics, and computational analysis. The postdoc will plan and execute experiments, analyze data, interpret, and present the results, supervise students as well as write scientific articles, initially under partial supervision but with greater independence going forward.

We are a young and dynamic research team with a well-established collaborative network. Our lab is located at Biomedicum, a top modern research building with a large repertoire of researchers and access to state-of-the-art infrastructure and facilities. Our group is also associated to the laboratory of Dr. Levens at the National Institutes of Health (US) and Dr. Shiraige at Tokyo University (JP). The candidate will greatly benefit from this interdisciplinary environment, immersion in a highly stimulating and supportive research community, unique infrastructure, a buzzing capital, and scenic nature at your doorstep.

This Postdoctoral Fellow position in the Division of Immunology, Department of Medical Biochemistry and Biophysics (MBB), will be part of Professor Qiang Pan-Hammarström’s research group. The group conducts research on the genetics of inborn errors of immunity, B cell biology, B-cell lymphomagenesis and immunotherapy. It consists of several PhD students, postdoctoral researchers, and senior scientists. We offer a stimulating scientific environment and a top research infrastructure both locally, at the department level, and institution level.

This interdisciplinary project leverages expertise in mitochondrial disease and molecular immunology to investigate the mechanisms and consequences of mitochondrial dysfunction in patients with inherited disorders and in animal models of mitochondrial pathology. The goal is to uncover novel insights into the role of mitochondria in human immunity through detailed molecular characterization of these disease models.

Joanna Rorbach’s lab: Our current research encompasses genetic, structural, and biochemical studies to understand the regulation of gene expression in mitochondria, often in the context of immunity (e.g. Shao et al. Nature Communications 2025; Zhang et al. JCI Insight 2023; Kruger et al. Nature Commun. 2023; Itoh et al. Nature, 2022 Cipullo et al. Nature Commun, 2024). The overall aim of the group is to combine these different areas of research to get insights into disease pathophysiology and to develop novel treatments. 

The successful candidate will join an international team of enthusiastic researchers at Department of Medical Biochemistry and Biophysics. Stockholm is a vibrant international megapolis with one of the highest quality of living standards in the world. Virtually everyone in Stockholm can speak English and English is the only working language of the groups.

Sickness behavior refers to the coordinated set of behavioral changes and subjective experiences that occur during acute infections. In the field of psychoneuroimmunology, it is assumed that sickness behavior supports immune function as part of an adaptive response. Yet, this hypothesis has not been tested in humans. The aim of the current project is to examine how sickness behavior influences immune responses during a common cold, induced under controlled laboratory conditions.

The PI of the project is Associate Prof Julie Lasselin. The project will be conducted in close collaboration with the Emergency Medicine Research Center led by Associate Prof Daniel Wilhelms, at Linköping University. Part of the data collection can be conducted at Linköping University.

The postdoctoral researcher will be responsible for developing and coordinating the project, including writing ethics applications and study preregistration, leading participant recruitment and data collection, conducting statistical analyses, and disseminating findings in recognized international journals. The role may also include contributing to the preparation of research grant applications to support future studies.

In addition, the postdoc is expected to participate in mentoring activities by supervising Master’s and/or PhD students and will be encouraged to take an active role in the group’s collaborative, interdisciplinary research environment. There will also be opportunities to develop independent research ideas related to the project and to engage in national and international collaborations.

We are seeking a highly motivated postdoctoral researcher in the field of molecular endocrine pathology, with a strong interest in translational cancer research, particularly focused on thyroid cancer. The successful candidate will actively contribute to research projects focused on uncovering the molecular mechanisms behind thyroid cancer dedifferentiation and resistance to conventional treatments. The project involves the integration of advanced transcriptomic techniques, including single-cell and spatial transcriptomics, along with proteomics, to discover new biomarkers and potential therapeutic targets. Complementary in vitro studies using established thyroid cancer cell lines will support the validation of key findings and enable the functional characterization of newly identified markers involved in thyroid cancer progression and dedifferentiation.

The ideal candidate will have solid expertise in molecular biology. Experience in omics-based data generation and a demonstrated ability to analyze, visualize, and interpret complex high-throughput datasets is considered a strong advantage. Prior experience with thyroid cancer models, endocrine tumors, or tumor heterogeneity is highly desirable. Excellent communication skills, a collaborative and proactive mindset, and the ability to work effectively within a multidisciplinary team are essential. This position requires a strong and balanced skill set in both wet lab techniques and computational/data-driven research.

The project offers an exciting opportunity to engage in cutting-edge research that combines discovery-based approaches such as transcriptomics and proteomics with mechanistic studies and functional validation. The successful candidate will work closely with a dedicated team of scientists in a dynamic and supportive environment.

The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are looking to recruit 7 outstanding postdoctoral research fellows. 

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. giving the fellows lot of opportunities to make new connections both within Karolinska Institutet and internationally in the field of diabetes and metabolism.