A single-cell spatial proteomic atlas of microglia in human brains revealed broad functional changes in Alzheimer’s disease.



Summary

A spatial proteomic atlas of microglia, built from single-cell analysis of human brain tissue, has revealed significant functional alterations in these cells in Alzheimer’s disease (AD). This comprehensive study provides a detailed map of protein expression within individual microglia across different brain regions affected by AD. The atlas highlights specific protein changes in microglia associated with disease progression, suggesting how these changes contribute to AD pathology. This research offers valuable insights into the role of microglia in AD and identifies potential therapeutic targets.

Read more…

This post is part of “Science and Technology News”, Follow for more…!!!

Credits: Source

Disclaimer