It’s been thought that T cells would only move into the brain in the case of a serious problem. New work shows otherwise…



Summary

Contrary to previous beliefs, T cells, a type of immune cell, regularly patrol the healthy brain, not just during disease. This research challenges the long-held assumption that the brain is largely immune-isolated. Scientists discovered that T cells constantly enter and exit the brain via the choroid plexus, a specialized brain structure. These T cells appear to monitor the brain environment, potentially contributing to its normal function and surveillance. This finding has significant implications for understanding brain health, aging, and neurodegenerative diseases where immune system interactions are crucial.

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