Lipid nanoparticles (LNPs) are tiny fat bubbles that are used to deliver medicines, genes, and RNA into cells. However, in some cases LNPs can cause harmful inflammation as a result of the process of RNA delivery.



Summary

Lipid nanoparticles (LNPs) are miniature spheres of fat employed for targeted delivery of therapeutics like medicines, genes, and RNA into cells. While effective, a significant drawback is their potential to trigger inflammation in the body. This inflammatory response is often linked to the RNA delivery process itself. Understanding and mitigating this unwanted inflammation is crucial for enhancing the safety and efficacy of LNP-based therapies.

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