When people take antibiotics, some of the dose is excreted with urine and feces and ends up in our wastewater. The presence of this low dose of antibiotic creates an opportunity for resistant bacteria to evolve.



Summary

Antibiotic use contributes to the presence of low-dose antibiotics in wastewater through excretion. This occurs when antibiotics consumed by people are not fully metabolized and are released into sewage systems via urine and feces. This low concentration of antibiotics in wastewater creates an environment where bacteria are exposed to the drugs, even if at sub-lethal levels. Such exposure provides a selective pressure, favoring the survival and proliferation of bacteria that possess or develop resistance mechanisms. Consequently, the wastewater environment becomes a breeding ground for antibiotic-resistant bacteria, posing a significant public health threat.

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