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Genetic bottlenecks help explain which cholera strains become pandemic pathogens



A new study sheds light on one of the great enigmas of microbiology: why only certain strains of common bacteria become pandemic pathogens.



Summary

A new study explores why some bacterial strains evolve into pandemic pathogens while others remain harmless. Researchers investigated the genetic and environmental factors that differentiate pandemic and non-pandemic strains of common bacteria. The research suggests that specific genetic mutations combined with favorable environmental conditions are crucial for triggering a pandemic. Understanding these triggers can aid in developing strategies for early detection and prevention of future bacterial pandemics by identifying potentially dangerous strains before they spread globally.

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