A neuronal mechanism pumps the brakes on pain, but failure of these brakes can cause long-lasting pain. The discovery could open new pain treatment paths.



Summary

Researchers have identified a neuronal mechanism that acts as a “brake” on pain signals. This system, when functioning correctly, prevents pain from becoming chronic. However, when these brakes fail, pain can persist long after the initial injury heals. This groundbreaking discovery suggests that boosting the activity of this pain-dampening mechanism could be a novel and effective strategy for developing new treatments for chronic pain conditions.

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