Viral infection Archives

Carboxylation switch – New Study

Dr AF Saeed Dr AF Saeed 30th July 2025

Nature Immunology, Published online: 29 July 2025; doi:10.1038/s41590-025-02249-w Carboxylation switch Summary A groundbreaking study published in Nature Immunology reveals a novel “carboxylation switch” mechanism in immune regulation. Researchers discovered that specific immune cells Read More

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Manipulation of the nucleotide pool in human, bacterial and plant

Dr AF Saeed Dr AF Saeed 29th July 2025

Nature Reviews Immunology, Published online: 29 July 2025; doi:10.1038/s41577-025-01206-w Modification of the nucleotide pool is emerging as key to innate immunity in animals, plants and bacteria. This Review explains how immune pathways conserved Read More

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Live vaccine development through targeted protein degradation – New Study

Dr AF Saeed Dr AF Saeed 24th July 2025

Nature Reviews Immunology, Published online: 24 July 2025; doi:10.1038/s41577-025-01212-y In this Tools of the Trade article, Qisi Zhang and Longlong Si describe a method for generating live attenuated vaccines that involves targeting viruses Read More

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IL-4 impairs the formation of skin-resident memory CD8<sup>+</sup> T cells

Dr AF Saeed Dr AF Saeed 14th July 2025

Nature Immunology, Published online: 14 July 2025; doi:10.1038/s41590-025-02207-6 Bromley and colleagues show that IL-4 decreases the responsiveness of CD8+ T cells to TGFβ, resulting in impaired formation of CD8+ TRM cells. Summary Bromley Read More

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FOXP3 dependence

Dr AF Saeed Dr AF Saeed 2nd July 2025

Nature Immunology, Published online: 30 June 2025; doi:10.1038/s41590-025-02213-8 FOXP3 dependence Summary A new study published in Nature Immunology reveals a crucial dependency on the transcription factor FOXP3 for the sustained suppressive function of Read More