Scientists have discovered that flossing between your teeth could one day help vaccinate you. By targeting a uniquely permeable gum tissue called the junctional epithelium, this new method stimulates immunity right where many infections enter: Read More
Tags :Vaccine
Education, Research & Positions
Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer:
Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results Summary The AMPLIFY-201 phase 1 trial evaluated a novel lymph node-targeted vaccine targeting the mKRAS mutation in patients with pancreatic and Read More
Education, Research & Positions
Defects in antigen processing and presentation: mechanisms, immune evasion and
Defects in antigen processing and presentation: mechanisms, immune evasion and implications for cancer vaccine development Summary Defects in antigen processing and presentation (APP) mechanisms are critical for immune surveillance and cancer control. These defects, arising Read More
The gut microbiota in cancer immunity and immunotherapy Summary The gut microbiota plays a crucial role in shaping both local and systemic immune responses, significantly impacting cancer development and response to immunotherapy. Specific bacterial species Read More
Science, Volume 389, Issue 6759, Page 455-457, July 2025. Summary Without knowing the specific content of the Science article from July 2025, I can provide a general summary based on the journal and format. A Science article in that Read More
Education, Research & Positions
Tick Troubles: Lyme Disease Persistence, Red Meat Allergy Spread, and
Ticks spread pathogenic infections, and surprisingly, immune reactions. New vaccine candidates may help reduce this risk. Summary Ticks are vectors of diseases, transmitting both pathogens and inducing immune reactions in hosts. This dual threat Read More
Education, Research & Positions
Live vaccine development through targeted protein degradation – New Study
Nature Reviews Immunology, Published online: 24 July 2025; doi:10.1038/s41577-025-01212-y In this Tools of the Trade article, Qisi Zhang and Longlong Si describe a method for generating live attenuated vaccines that involves targeting viruses Read More
Education, Research & Positions
Engineers transform dental floss into needle-free vaccine – New Study
New method places inactivated viruses directly into mice’s gums Summary A novel method directly applies inactivated viruses to mice’s gums, offering a potentially efficient and less invasive way to trigger immune responses. Unlike Read More
Education, Research & Positions
Oncolytic virus-mediated p53 activation boosts the antitumor immunity of a
Oncolytic virus-mediated p53 activation boosts the antitumor immunity of a p53-transduced dendritic cell vaccine Summary This research explores combining oncolytic viruses and p53-enhanced dendritic cell (DC) vaccines to improve cancer immunotherapy. Specifically, DCs Read More
Education, Research & Positions
Conjugate Vaccine Mechanisms, Design, and Immunological Memory – New Study
By linking bacterial polysaccharides to carrier proteins, conjugate vaccines transform weak antigens into triggers of lasting T cell-dependent immunity. Summary Conjugate vaccines boost the immune system by linking bacterial polysaccharides (sugars) to carrier proteins. Bacterial Read More
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