Nature Immunology, Published online: 13 August 2025; doi:10.1038/s41590-025-02245-0 Circadian oscillation of gene expression controls gut tissue homeostasis. The transcription factors REV-ERBα and REV-ERBβ, which control the expression of clock genes, are also central Read More
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In a model of chronic NAD+ depletion that mimics aging, mitochondria are revealed as a rheostat of cellular NAD+ levels. Summary Mitochondria act as cellular regulators (“rheostats”) of NAD+ levels, especially during chronic NAD+ depletion, Read More