ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation Summary ULBP2 CAR-T cells show promise in improving gastric cancer immunotherapy by targeting and killing tumor cells and simultaneously disrupting the tumor microenvironment. The Read More
Surprising role of CMV in shaping outcomes of immunotherapy for melanoma — chronic infection yields favourable survival Summary Cytomegalovirus (CMV), a common chronic virus, surprisingly improves immunotherapy outcomes in melanoma patients. Research suggests that individuals with Read More
Mobilizing antigen-presenting mast cells in anti-PD-1-refractory triple-negative breast cancer: a phase 2 trial Summary This phase 2 trial explores a novel approach to overcome resistance to anti-PD-1 immunotherapy in triple-negative breast cancer (TNBC). Researchers aim to Read More
Nature Reviews Immunology, Published online: 16 June 2025; doi:10.1038/s41577-025-01193-y Iron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlights how iron regulates innate Read More
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