Science, Volume 389, Issue 6759, Page 468-469, July 2025. Summary Without specific content, I can only provide a general summary. Science, Volume 389, Issue 6759, published in July 2025, likely contains peer-reviewed research articles, perspectives, and news relevant to various scientific Read More
Tags :targeting
Nature Immunology, Published online: 29 July 2025; doi:10.1038/s41590-025-02248-x Targeting CAFs Summary Cancer-associated fibroblasts (CAFs) play a crucial role in the tumor microenvironment, influencing cancer progression, metastasis, and immune evasion. This Nature Immunology article Read More
Education, Research & Positions
Targeting gut microbiota and arginase boosts MEK inhibitors’ enhancement of
Targeting gut microbiota and arginase boosts MEK inhibitors’ enhancement of antitumour immunity via MHC-I upregulation in colorectal cancer Summary MEK inhibitors, while promising for colorectal cancer (CRC) treatment, often face limited efficacy. This study reveals Read More
Education, Research & Positions
Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer
Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy Summary Nanobody-based bispecific antibody engagers offer a promising avenue for cancer immunotherapy. These molecules combine the target specificity of nanobodies, small and stable antibody Read More
Education, Research & Positions
Dual targeting of tumoral cells and immune microenvironment by blocking
Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway Summary Blocking the IL-33/IL1RL1 pathway presents a promising dual approach for cancer therapy. IL-33, released by stressed or Read More
Education, Research & Positions
Targeting ribosomes reprograms the tumour microenvironment and augments cancer immunotherapy
Targeting ribosomes reprograms the tumour microenvironment and augments cancer immunotherapy Summary Targeting ribosomes, the protein synthesis machinery of cells, can significantly alter the tumor microenvironment (TME) and enhance cancer immunotherapy. Dysfunctional ribosomes in cancer cells Read More
Education, Research & Positions
Targeting mTORC2 in lung squamous cell carcinoma improves anti-tumor immunity
Targeting mTORC2 in lung squamous cell carcinoma improves anti-tumor immunity through the PSGL-1-VISTA axis Summary Targeting mTORC2 in lung squamous cell carcinoma (LUSC) enhances anti-tumor immunity by modulating the PSGL-1-VISTA pathway. Specifically, mTORC2 Read More
Education, Research & Positions
Therapeutic targeting of mismatch repair-deficient cancers – New Study
Therapeutic targeting of mismatch repair-deficient cancers Summary Mismatch repair deficient (dMMR) cancers, characterized by high microsatellite instability (MSI-H), represent a distinct subset with unique vulnerabilities. Lacking proper DNA repair mechanisms, they accumulate mutations, leading to Read More
Education, Research & Positions
Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in
Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in recurrent glioblastoma: a phase 1 trial Summary This phase 1 clinical trial investigated the safety and efficacy of intracerebroventricular (ICV) administration of bivalent CAR T cells Read More
Education, Research & Positions
Immune-checkpoint targeting drug conjugates: a novel class of promising therapeutic
Immune-checkpoint targeting drug conjugates: a novel class of promising therapeutic agents for cancer treatment Summary Immune-checkpoint targeting drug conjugates (ICT-DCs) represent a promising new strategy in cancer treatment. These conjugates combine the precision of immune Read More
Site Logo
Powered by AI
New Journal Citation Reports (JCR) 2025
All-Time Views
1 Million+ Views and Counting..!
Follow me on Linkedin for Latest Jobs and Scholarships
Subscribe Youtube
Celebrating 7 Years
It has been 7 years since it was launched in late July 2018, and it is moving forward. Appreciate all the respected visitors! Please share this site with your friends to push science forward and improve human health.
Site Trust Score
Google Safe
