Researchers discover that cancer itself can trigger signs of aging, creating opportunities to address cancer-related health complications. A recent investigation conducted by researchers at Moffitt Cancer Center has shown that lymphoma can speed up the Read More
Tags :T-cells
CD160+CD8+ T cells for improved immunotherapy Summary CD160+CD8+ T cells are a subset of cytotoxic T lymphocytes (CTLs) with enhanced antitumor activity. CD160, an activating receptor, distinguishes these cells and contributes to their Read More
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer Summary CD160, a surface receptor on CD8+ T cells, plays a crucial role in resistance to anti-PD-1 immunotherapy in colorectal cancer (Read More
Nature Reviews Immunology, Published online: 08 September 2025; doi:10.1038/s41577-025-01219-5 Functional and metabolic properties of innate-like T cells — namely, iNKT cells, MAIT cells and some γδ T cells — differ from those of conventional T cells. Read More
This Widely-Used Antidepressant Could Be a Powerful New Weapon Against
Antidepressants help immune cells fight cancer. They may improve therapy effectiveness. A commonly prescribed antidepressant may also strengthen the body’s defenses against cancer, according to new research from UCLA. The study, published in Cell, Read More
Regulatory KIR<sup>+</sup>CD8<sup>+</sup> T cells in pregnancy – New Study
Nature Reviews Immunology, Published online: 01 September 2025; doi:10.1038/s41577-025-01225-7 Populations of regulatory KIR+CD8+ T cells expand during pregnancy and can promote maternal tolerance to the developing fetus. Summary A Nature Reviews Immunology Read More
Nature Reviews Immunology, Published online: 01 September 2025; doi:10.1038/s41577-025-01224-8 B cells that expand following infection with EBV can colonize the brain, where they recruit activated T cells that have potential to cause neuronal Read More
Nature Immunology, Published online: 29 August 2025; doi:10.1038/s41590-025-02274-9 T cells in space and time Summary A Nature Immunology article published on August 29, 2025, explores the dynamic behavior of T cells within the context of Read More
Glucose drives T cell signaling. Stronger signals mean better cancer defense. For the body’s disease-fighting T cells, glucose is much more than just a simple sugar rush. Scientists at the Van Andel Institute have Read More
Expanding the cytokine receptor alphabet reprograms T cells into diverse
Expanding the cytokine receptor alphabet reprograms T cells into diverse states Summary T cells, traditionally defined by a limited set of cytokine receptors, can be drastically reprogrammed by expanding this “receptor alphabet.” Research demonstrates that Read More