ICANS and mortality after CAR-T therapy for NHL patients can be predicted using physical function measures of falls, balance and strength deficits, and use of an assistive device Summary Physical function assessments can predict mortality Read More
Tags :Stem Cells
CD160+CD8+ T cells for improved immunotherapy Summary CD160+CD8+ T cells are a subset of cytotoxic T lymphocytes (CTLs) with enhanced antitumor activity. CD160, an activating receptor, distinguishes these cells and contributes to their Read More
Education, Research & Positions
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer Summary CD160, a surface receptor on CD8+ T cells, plays a crucial role in resistance to anti-PD-1 immunotherapy in colorectal cancer (Read More
Researchers have created a remarkable new approach to repairing spinal cord injuries by merging 3D printing, stem cells, and lab-grown tissues. They engineered tiny scaffolds that guide stem cells to form nerve fibers capable of Read More
The impact of social determinants of health on outcomes of brexucabtagene autoleucel in adults with relapsed/refractory B-cell acute lymphoblastic leukemia Summary Social determinants of health (SDOH) significantly impact outcomes in adults with relapsed/refractory Read More
Safety and efficacy of autologous humanized CD19 CAR-T cell therapy for relapsed/refractory B-cell non-Hodgkin lymphoma Summary Autologous CD19 CAR-T cell therapy shows promise for treating relapsed/refractory B-cell non-Hodgkin lymphoma (r/r B-NHL). Studies Read More
Education, Research & Positions
Post-transplantation cyclophosphamide and antithymocyte globulin in 8/10 HLA-mismatched unrelated donor
Post-transplantation cyclophosphamide and antithymocyte globulin in 8/10 HLA-mismatched unrelated donor transplantation: the analysis on behalf of the transplant complications working party of the EBMT Summary A study by the EBMT’s Transplant Complications Working Party analyzed Read More
Empowering hypoxia to convert cold tumors into hot tumors for breast cancer immunotherapy Summary Recent research explores harnessing hypoxia, a common characteristic of “cold” tumors (those resistant to immunotherapy), to enhance breast cancer immunotherapy. By Read More
The liver metabolizes dietary galactose to fuel antitumour T cell immunity Summary Dietary galactose, often overlooked, plays a crucial role in fueling anti-tumor T cell responses, particularly when metabolized in the liver. The liver’s Read More
Nature Reviews Immunology, Published online: 24 July 2025; doi:10.1038/s41577-025-01203-z This Review by Poirier highlights the intrinsic mechanisms that protect stem cells from infection. The author also explains how stem cell populations in different Read More
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