The liver metabolizes dietary galactose to fuel antitumour T cell immunity Summary Dietary galactose, often overlooked, plays a crucial role in fueling anti-tumor T cell responses, particularly when metabolized in the liver. The liver’s Read More
Tags :Stem Cells
Nature Reviews Immunology, Published online: 24 July 2025; doi:10.1038/s41577-025-01203-z This Review by Poirier highlights the intrinsic mechanisms that protect stem cells from infection. The author also explains how stem cell populations in different Read More
ICANS risk model in CD19 CAR-T therapy: insights from serum and CSF cytokine profiling Summary This study explores the predictive power of the Immune Cell-Associated Neurotoxicity Syndrome (ICANS) risk model in CD19 CAR-T therapy patients Read More
Education, Research & Positions
MARCO expression on myeloid-derived suppressor cells is essential for their
MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression Summary Myeloid-derived suppressor cells (MDSCs) require MARCO expression to properly differentiate and exert their immunosuppressive functions. MARCO, a scavenger receptor, plays a Read More
Education, Research & Positions
Metabolic reprogramming in colorectal cancer: a review of aerobic glycolysis
Metabolic reprogramming in colorectal cancer: a review of aerobic glycolysis and its therapeutic implications for targeted treatment strategies Summary Colorectal cancer (CRC) cells exhibit metabolic reprogramming, primarily through aerobic glycolysis, also known as the Warburg Read More
Education, Research & Positions
Outcome of second allogeneic hematopoietic cell transplantation in adult patients
Outcome of second allogeneic hematopoietic cell transplantation in adult patients with relapsed B-cell acute lymphoblastic leukemia in the era of new immunotherapeutic agents Summary This study investigates the effectiveness of second allogeneic hematopoietic cell transplantation (Read More
Optimization of CAR T-cell dose: a debated unresolved issue Summary Optimizing the dose of CAR T-cells remains a contentious issue in immunotherapy. While higher doses theoretically offer enhanced tumor eradication, they also increase the risk Read More
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