Nature Immunology, Published online: 12 August 2025; doi:10.1038/s41590-025-02246-z A complex of the NF-κB family member p52 and the transcription factor ETS1 is required for B cell germinal center responses to T cell-dependent Read More
Tags :responses
Convergence and divergence of individual immune responses over the life
Science, Volume 389, Issue 6760, Page 604-609, August 2025. Summary Without knowing the specific content of Science, Volume 389, Issue 6760, pages 604-609 (August 2025), a summary can only be a placeholder. Assume this section contains a groundbreaking article on AI-driven Read More
Anticipation of Infection, Even in Virtual Reality, Triggers Immune Responses
A virtual reality study showed that the brain can detect potential infectious threats and prime the immune system, offering fresh insights into behavioral immunity. Summary A recent virtual reality study revealed a surprising connection between Read More
Exercise induces metabolic changes in the gut microbiota that enhance
Nature Reviews Immunology, Published online: 28 July 2025; doi:10.1038/s41577-025-01217-7 Exercise promotes changes in the gut microbiota that enhance anti-tumour T cell responses. Summary A Nature Reviews Immunology article (published July 28, 2025) highlights the connection Read More
Endogenous T cell responses to fusion-derived neoantigens in pediatric acute
Endogenous T cell responses to fusion-derived neoantigens in pediatric acute leukemias Summary Pediatric acute leukemias, particularly those with fusion oncogenes, can generate unique neoantigens derived from the fusion point. Research has shown that the immune Read More
Combination of pembrolizumab and radiotherapy induces systemic antitumor immune responses
Combination of pembrolizumab and radiotherapy induces systemic antitumor immune responses in immunologically cold non-small cell lung cancer Summary A study demonstrates that combining pembrolizumab, an immunotherapy drug, with radiotherapy can trigger systemic anti-tumor immune responses Read More
Single-cell spatial analysis with Xenium reveals anti-tumour responses of CXCL13 + T
Single-cell spatial analysis with Xenium reveals anti-tumour responses of CXCL13 + T and CXCL9+ cells after radiotherapy combined with anti-PD-L1 therapy Summary A study using single-cell spatial analysis with the Xenium platform investigated the effects of Read More
Bispecific killer cell engager-secreting CAR-T cells redirect natural killer specificity
Bispecific killer cell engager-secreting CAR-T cells redirect natural killer specificity to enhance antitumour responses Summary Genetically engineered CAR-T cells can be modified to secrete bispecific killer cell engagers (BiKEs) targeting both tumor-associated antigens and NK Read More
Intratumoral expression of IL-12 and CD40 ligand (CD154) from plasmids
Intratumoral expression of IL-12 and CD40 ligand (CD154) from plasmids generates antitumor responses that eliminate tumoral T regs Summary Delivering plasmids encoding IL-12 and CD40L (CD154) directly into tumors can effectively trigger antitumor immunity. Read More
Coupled, decoupled, and abrupt responses of vegetation to climate across
Science, Volume 389, Issue 6755, Page 64-68, July 2025. Summary Without knowing the specific article published in Science, Volume 389, Issue 6755 (July 2025), I can only provide a general summary. This issue of Science, published in July 2025, likely contains cutting-edge Read More