Cancer immunotherapy has advanced the field of medicine and cancer care. Specifically, immunotherapy refers to the targeted treatment of the immune system. Summary Cancer immunotherapy is a revolutionary approach that harnesses the power of the Read More
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Metabolic reprogramming in colorectal cancer: a review of aerobic glycolysis
Metabolic reprogramming in colorectal cancer: a review of aerobic glycolysis and its therapeutic implications for targeted treatment strategies Summary Colorectal cancer (CRC) cells exhibit metabolic reprogramming, primarily through aerobic glycolysis, also known as the Warburg Read More
Suppression of multiple mouse models of refractory malignancies by reprogramming
Suppression of multiple mouse models of refractory malignancies by reprogramming IL-18 ligand-receptor interaction Summary Researchers developed a novel immunotherapeutic strategy that reprograms the IL-18 pathway to combat refractory malignancies in mice. By engineering a “decoy” Read More
Metabolic reprogramming via FOXP3 engineering: A Novel strategy to enhance
Metabolic reprogramming via FOXP3 engineering: A Novel strategy to enhance CAR-T cell efficacy in solid tumors Summary Engineering CAR-T cells with the transcription factor FOXP3 can reprogram their metabolism to improve effectiveness against solid tumors. Read More