Nature Immunology, Published online: 13 August 2025; doi:10.1038/s41590-025-02245-0 Circadian oscillation of gene expression controls gut tissue homeostasis. The transcription factors REV-ERBα and REV-ERBβ, which control the expression of clock genes, are also central Read More
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Education, Research & Positions
Circadian circuits control plasticity of group 3 innate lymphoid cells
Nature Immunology, Published online: 13 August 2025; doi:10.1038/s41590-025-02240-5 Colonna and colleagues show that the clock genes encoding REV-ERBα and REV-ERBβ maintain ILC3 functions in the gut by controlling the expression of RORγt. Read More
Education, Research & Positions
Identification of the Notch ligand DLK1 as an immunotherapeutic target
Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma Summary Adrenocortical carcinoma (ACC) is an aggressive cancer with limited treatment options. This research Read More