T cells engineered to target a shared β-catenin mutation eradicate solid tumors in mice Summary Genetically engineered T cells targeting a specific mutation in the β-catenin protein have shown remarkable success in eradicating solid tumors Read More
Tags :Mice
Researchers have discovered that brain cancer cells reprogram their sugar metabolism, a vulnerability that can be exploited in mice to impede tumor growth and enhance therapeutic outcomes. Glioblastomas are the most aggressive type of malignant Read More
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Stanford Scientists Successfully Reverse Autism Symptoms in Mice – New
Overactivity in the reticular thalamic nucleus was shown to cause autism-like behaviors in mice. Drugs that reduce this activity reversed the symptoms. Researchers at Stanford Medicine studying the neurological basis of autism spectrum disorder have Read More
Nature Immunology, Published online: 29 August 2025; doi:10.1038/s41590-025-02273-w Humanized mice for MS studies Summary A new study in Nature Immunology (August 29, 2025) highlights the development of humanized mice for studying Multiple Sclerosis (MS). The Read More
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Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote
Science, Volume 389, Issue 6760, August 2025. Summary Without specific articles or content within the Science issue, a precise summary is impossible. However, a general summary could be: The August 2025 issue of Science (Volume 389, Issue 6760) likely presents cutting-edge Read More
Education, Research & Positions
Conserved noncoding cis elements associated with hibernation modulate metabolic and
Science, Volume 389, Issue 6759, Page 501-507, July 2025. Summary Without knowing the specific content of the Science issue mentioned, it’s impossible to provide a truly accurate summary. However, I can offer a general summary based on Read More
Excessive levels of GABA released by astrocytes impair the brain’s ability to extinguish fear responses in PTSD, but a newly identified drug target offers promising hope for treatment. Many people with post-traumatic stress disorder (Read More
Education, Research & Positions
Microglia replacement halts the progression of microgliopathy in mice and
Science, Volume 389, Issue 6756, July 2025. Summary Please provide the content you would like me to summarize. I need the articles, abstracts, or any text related to the Science journal, Volume 389, Issue 6756, from July 2025, to give you Read More
Education, Research & Positions
Orchestrating intratumoral DC-T cell immunity for enhanced tumor control via
Orchestrating intratumoral DC-T cell immunity for enhanced tumor control via radiotherapy-activated TLR7/8 prodrugs in mice Summary Researchers developed a novel approach combining radiotherapy (RT) with TLR7/8 agonist prodrugs activated by RT within tumors in mice. Read More
Mice with a diverse human T cell receptor repertoire selected on multiple HLA class I molecules Summary Mice were engineered to express a diverse range of human T cell receptors (TCRs) selected based on their Read More
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