Researchers at UC San Francisco have uncovered a surprising culprit in brain aging: a protein called FTL1. In aging mice, too much of this protein weakened memory and disrupted neural connections. But when scientists blocked Read More
Tags :memory
Mitochondria are tiny structures inside our cells that supply the energy our bodies need to survive, and scientists are steadily uncovering more about how they work. A new study in Nature Neuroscience, led by researchers Read More
Learning a motor task alters brain activity during a nap, which promotes neural plasticity and can predict how much a person’s ability will improve. Summary Napping after learning a motor skill improves performance Read More
T cells require mitochondria to proliferate, function and generate memory
Nature Immunology, Published online: 22 July 2025; doi:10.1038/s41590-025-02226-3 Using genetic modifications to dissect mitochondrial functions, we found that, on acute stimulation, CD8+ T cells require mitochondrial metabolism to sustain proliferation and prevent exhaustion. Read More
Conjugate Vaccine Mechanisms, Design, and Immunological Memory – New Study
By linking bacterial polysaccharides to carrier proteins, conjugate vaccines transform weak antigens into triggers of lasting T cell-dependent immunity. Summary Conjugate vaccines boost the immune system by linking bacterial polysaccharides (sugars) to carrier proteins. Bacterial Read More
IL-4 impairs the formation of skin-resident memory CD8<sup>+</sup> T cells
Nature Immunology, Published online: 14 July 2025; doi:10.1038/s41590-025-02207-6 Bromley and colleagues show that IL-4 decreases the responsiveness of CD8+ T cells to TGFβ, resulting in impaired formation of CD8+ TRM cells. Summary Bromley Read More
Alzheimer’s Iceberg: 200+ Hidden Proteins That May Be Quietly Destroying
A groundbreaking study has revealed over 200 misfolded proteins in the brains of aging rats with cognitive impairment, far beyond the well-known amyloid and tau plaques. These newly identified proteins don’t form the typical clumps Read More
University of Birmingham – Development and Alumni Relations Office<br />Salary: £32,546 to £35,116. Grade 6 Read more… Credits: jobs.ac.uk DisclaimerRead More
Science, Volume 389, Issue 6755, July 2025. Summary To summarize a non-existent issue of a journal is impossible. Science is a well-respected scientific journal, but there’s no Issue 6755 scheduled for July 2025 yet. Without the actual content, I Read More
Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and
Different tumour-resident memory T-cell subsets regulate responses to anti-PD-1 and anti-CTLA-4 cancer immunotherapies Summary Tumour-resident memory T cells (Trm) are critical for effective cancer immunotherapy, but their heterogeneity and specific roles remain unclear. Research reveals Read More