Slaying the pre-TCR beast Summary "Slaying the pre-TCR beast" likely refers to overcoming challenges and inefficiencies in traditional Request for Change (RFC) processes before implementing a more streamlined and automated Technical Change Request (Read More
Tags :Leukaemia
Nature Immunology, Published online: 05 September 2025; doi:10.1038/s41590-025-02269-6 The pre-T cell receptor is essential for T cell development. It is also an emerging immunotherapy target. Summary The pre-T cell receptor (pre-TCR) is crucial Read More
Education, Research & Positions
The unfolded protein response influences therapy outcome and disease progression
The unfolded protein response influences therapy outcome and disease progression in chronic lymphocytic leukaemia Summary Chronic lymphocytic leukemia (CLL) cells rely on the unfolded protein response (UPR), a cellular stress response pathway, to survive. The Read More
Education, Research & Positions
Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T
Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukaemia Summary Researchers have developed a bioengineered “trial-on-chip” system that mimics the human immune system to test CAR T-cell therapy effectiveness against Read More
Education, Research & Positions
The European Conference on Infections in Leukaemia (ECIL-10) guidelines for
The European Conference on Infections in Leukaemia (ECIL-10) guidelines for COVID-19 should take convalescent plasma into proper consideration Summary The upcoming ECIL-10 guidelines for COVID-19 management in leukemia patients should thoroughly evaluate the potential benefits Read More
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