Nature Immunology, Published online: 22 September 2025; doi:10.1038/s41590-025-02285-6 The authors spatially and functionally map innate lymphoid cells in the human female genital tract at homeostasis, uncovering tissue-specific and subset-specific distribution and functions, and Read More
Tags :Innate lymphoid cells
Nature Immunology, Published online: 18 September 2025; doi:10.1038/s41590-025-02275-8 The effector fates of innate lymphoid cells (ILCs) are epigenetically imprinted early in ontogeny through the selective loss of DNA methylation at signature genes encoding Read More
Nature Reviews Immunology, Published online: 29 August 2025; doi:10.1038/s41577-025-01220-y A study by Bhattarai et al. in Nature Immunology reports that ILC3-to-ILC1 plasticity in the gut is regulated by circadian clock proteins. Summary Read More
Education, Research & Positions
CGRP-related neuropeptide adrenomedullin 2 promotes tissue-protective ILC2 responses and limits
Nature Immunology, Published online: 15 August 2025; doi:10.1038/s41590-025-02243-2 Artis and colleagues show that enteric neurons produce CGRP-related ADM2 to promote intestinal tissue-protective functions in ILC2s. Summary A new study in Nature Immunology Read More
Nature Immunology, Published online: 13 August 2025; doi:10.1038/s41590-025-02245-0 Circadian oscillation of gene expression controls gut tissue homeostasis. The transcription factors REV-ERBα and REV-ERBβ, which control the expression of clock genes, are also central Read More
Education, Research & Positions
Circadian circuits control plasticity of group 3 innate lymphoid cells
Nature Immunology, Published online: 13 August 2025; doi:10.1038/s41590-025-02240-5 Colonna and colleagues show that the clock genes encoding REV-ERBα and REV-ERBβ maintain ILC3 functions in the gut by controlling the expression of RORγt. Read More
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