Nature Immunology, Published online: 09 September 2025; doi:10.1038/s41590-025-02278-5 Cholesterol-dependent cytolysins produced by diverse bacterial pathogens are internalized by host cells and translocate to the trans-Golgi network (TGN). They remodel the TGN into a Read More
Nature Immunology, Published online: 05 September 2025; doi:10.1038/s41590-025-02277-6 Chen and colleagues show that type A cholesterol-dependent cytolysins, a group of bacteria pore-forming toxins, translocate to the trans-Golgi network to remodel it into a Read More
Nature Immunology, Published online: 18 August 2025; doi:10.1038/s41590-025-02230-7 Latz et al. review the molecular mechanisms that drive NLRP3 inflammasome activation and regulation, and discuss emerging targeting strategies. Summary In a review published in Read More
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