Nature Immunology, Published online: 25 July 2025; doi:10.1038/s41590-025-02242-3 When dendritic cells migrate through narrow gaps, they transiently assemble a mechanosensitive actin structure in front of their nucleus. This structure pushes outward against the Read More
Tags :Infectious diseases
Nature Immunology, Published online: 25 July 2025; doi:10.1038/s41590-025-02217-4 Sajti and colleagues identify TREM2 as a critical factor in myeloid cells in response to hyperoxia-induced lung injury in neonates, finding that TREM2 deficiency protects Read More
Education, Research & Positions
The transcription complex p52–ETS1 is essential for germinal center formation
Nature Immunology, Published online: 25 July 2025; doi:10.1038/s41590-025-02236-1 Tergaonkar and colleagues identify a noncanonical interaction between the NF-κB transcription factor family member p52 and the ETS family member ETS1. They find that Read More
Nature Immunology, Published online: 24 July 2025; doi:10.1038/s41590-025-02205-8 Single-cell spatial proteomics paired with chromatin accessibility mapping identifies a diverse range of human microglial immune states. In Alzheimer’s disease, hippocampal microglia tend to Read More
Education, Research & Positions
Secretogranin 2 binds LILRB4 resulting in immunosuppression – New Study
Nature Immunology, Published online: 24 July 2025; doi:10.1038/s41590-025-02233-4 Here the authors identify the granin hormone SCG2 as a ligand for the inhibitory receptor LILRB4. They show that SCG2 released from tumors can suppress Read More
Education, Research & Positions
Early methionine availability attenuates T cell exhaustion – New Study
Nature Immunology, Published online: 23 July 2025; doi:10.1038/s41590-025-02223-6 The tumor environment is nutrient deficient. Here the authors show that early availability of methionine is critical for optimal T cell activation and prevents T Read More
Education, Research & Positions
Transcription factors TCF4 and KLF4 respectively control the development of
Nature Immunology, Published online: 23 July 2025; doi:10.1038/s41590-025-02208-5 Here Zhu et al. investigate the ontogeny of type 2 dendritic cells (DC2s) in mice. Using Klf4 expression to distinguish conventional DC precursors from plasmacytoid Read More
Education, Research & Positions
T cells require mitochondria to proliferate, function and generate memory
Nature Immunology, Published online: 22 July 2025; doi:10.1038/s41590-025-02226-3 Using genetic modifications to dissect mitochondrial functions, we found that, on acute stimulation, CD8+ T cells require mitochondrial metabolism to sustain proliferation and prevent exhaustion. Read More
Education, Research & Positions
Spatial proteomics of Alzheimer’s disease-specific human microglial states – New
Nature Immunology, Published online: 22 July 2025; doi:10.1038/s41590-025-02203-w In this Resource paper, the authors use MIBI spatial proteomics to map microglial cell states in brains from cognitively normal humans and those with Alzheimer’Read More
Education, Research & Positions
LARP4-mediated hypertranslation drives T cell dysfunction in tumors – New
LARP4-mediated hypertranslation drives T cell dysfunction in tumors Summary LARP4, an RNA-binding protein, plays a significant role in tumor-induced T cell dysfunction. Researchers discovered that within tumors, T cells exhibit increased LARP4 expression. This Read More
Site Logo
Powered by AI
New Journal Citation Reports (JCR) 2025
All-Time Views
1 Million+ Views and Counting..!
Follow me on Linkedin for Latest Jobs and Scholarships
Subscribe Youtube
Celebrating 7 Years
It has been 7 years since it was launched in late July 2018, and it is moving forward. Appreciate all the respected visitors! Please share this site with your friends to push science forward and improve human health.
Site Trust Score
Google Safe
