Tags :Infectious diseases
Nature Immunology, Published online: 24 June 2025; doi:10.1038/s41590-025-02198-4 McGavern and colleagues identified a CD8+ T cell population that expresses GZMK in ʽtau-richʼ brains, where it may play a protective role against neurodegeneration. Summary Read More
Multiscale dynamic immunomodulation by a nanoemulsified Trojan-TLR7/8 adjuvant for robust protection against heterologous pandemic and endemic viruses Summary A novel nanoemulsion adjuvant, encapsulating a TLR7/8 agonist, was developed for enhanced and broad-spectrum antiviral immunity. This “Read More
Nature Immunology, Published online: 25 June 2025; doi:10.1038/s41590-025-02209-4 We identify a clonally expanded subset of granzyme K-expressing CD8+ T cells that establish residency in the central nervous system, where they target microglia and Read More
Nature Reviews Immunology, Published online: 18 June 2025; doi:10.1038/s41577-025-01191-0 During pregnancy, innate immune mechanisms at the maternal–fetal interface are important for protecting the developing fetus from pathogens. However, excessive immune activation can Read More