GD2TIF cells as a platform for single-dose and long-term delivery of biologics Summary GD2TIF cells, genetically engineered to express therapeutic molecules in response to tumor-specific GD2 disialoganglioside, hold promise for single-dose, long-term biologic Read More
Tags :immunotherapy
Education, Research & Positions
Novel Antibody Response Improves Immunotherapy in Cancer Patients – New
Cancer treatment has progressed over the last century. Specifically, the advent of immunotherapy has revolutionized how physicians treat patients. The goal Summary Cancer treatment has dramatically evolved, particularly with the rise of immunotherapy. Immunotherapy aims Read More
Education, Research & Positions
Mitochondrial Enzyme Sensitizes Solid Tumors to Immunotherapy – New Study
Tumors adapt to their environment to avoid detection. As different cancer treatments progress, tumors mutate and become resistant. Various markers are expr Summary Tumors are adept at evading detection and treatment by adapting to their Read More
Education, Research & Positions
Adding Dual Immunotherapy to Chemoradiation for Treating Rectal Cancer –
Immune checkpoint inhibitors (ICIs) have revolutionized the field of cancer immuno-oncology. ICIs act on cancer cells by blocking the interaction bet Summary Immune checkpoint inhibitors (ICIs) are a groundbreaking cancer therapy that boosts the Read More
Glucose drives T cell signaling. Stronger signals mean better cancer defense. For the body’s disease-fighting T cells, glucose is much more than just a simple sugar rush. Scientists at the Van Andel Institute have Read More
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Clonal diversity shapes the tumour microenvironment leading to distinct immunotherapy
Clonal diversity shapes the tumour microenvironment leading to distinct immunotherapy responses in metastatic urothelial carcinoma Summary Metastatic urothelial carcinoma (mUC) exhibits varying responses to immunotherapy, and clonal diversity within tumors plays a significant role in Read More
Education, Research & Positions
Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles
Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles to establish T-cell tolerance Summary Engineering allogeneic CAR-T cells that retain their T cell receptor (TCR) could overcome challenges of current CAR-T therapies. By understanding Read More
Education, Research & Positions
Directed evolution-based discovery of ligands for in vivo restimulation of
Directed evolution-based discovery of ligands for in vivo restimulation of chimeric antigen receptor T cells Summary Researchers have developed a directed evolution approach to discover ligands that can specifically restimulate chimeric antigen receptor (CAR) T Read More
Education, Research & Positions
Ultrasound-enhanced Pt-coordinated polymer immunopotentiators and heterogenic fusion membrane-based multifunctional tumor
Ultrasound-enhanced Pt-coordinated polymer immunopotentiators and heterogenic fusion membrane-based multifunctional tumor vaccine nanoplatforms for melanoma treatment Summary This research explores a novel approach to melanoma treatment combining ultrasound-enhanced immunopotentiators and a multifunctional tumor vaccine nanoplatform. The Read More
Education, Research & Positions
Cascade amplification of therapeutic payloads for cancer immunotherapy – New
Cascade amplification of therapeutic payloads for cancer immunotherapy Summary “Cascade amplification of therapeutic payloads” in cancer immunotherapy refers to strategies designed to enhance the efficacy of delivered drugs or immunomodulatory agents within the tumor microenvironment. Read More
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