The liver metabolizes dietary galactose to fuel antitumour T cell immunity Summary Dietary galactose, often overlooked, plays a crucial role in fueling anti-tumor T cell responses, particularly when metabolized in the liver. The liver’s Read More
Tags :Immunosurveillance
Education, Research & Positions
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds
Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function Summary This study investigates the relationship between the functional avidity of anti-B7H3 CAR-T cells and the antigen density required Read More
Education, Research & Positions
Anti-tumor immunity is boosted by loss of TGFβ-driven tissue residency
Nature Immunology, Published online: 29 July 2025; doi:10.1038/s41590-025-02224-5 Tumor-infiltrating CD8+ T cells acquire HOBIT expression and features of tissue-resident memory cells. This TGFβ-driven process is dispensable for tumor control by immune checkpoint Read More
Education, Research & Positions
Autoantibody spark response predicts treatment outcome in patients receiving chemoradiation
Autoantibody spark response predicts treatment outcome in patients receiving chemoradiation followed by durvalumab therapy Summary A study revealed that the development of new autoantibodies, termed “autoantibody spark,” following chemoradiation therapy (CRT) predicts the effectiveness of Read More
Education, Research & Positions
The microbiota in radiotherapy-induced cancer immunosurveillance – New Study
The microbiota in radiotherapy-induced cancer immunosurveillance Summary Radiotherapy (RT) can trigger anti-tumor immune responses, a process known as immunosurveillance. The gut microbiota plays a crucial role in modulating this process. RT-induced changes in the gut Read More
Education, Research & Positions
Intratumoral expression of IL-12 and CD40 ligand (CD154) from plasmids
Intratumoral expression of IL-12 and CD40 ligand (CD154) from plasmids generates antitumor responses that eliminate tumoral T regs Summary Delivering plasmids encoding IL-12 and CD40L (CD154) directly into tumors can effectively trigger antitumor immunity. Read More
Education, Research & Positions
Chemosensor receptors are lipid-detecting regulators of macrophage function in cancer
Nature Immunology, Published online: 30 June 2025; doi:10.1038/s41590-025-02191-x Tumor-associated macrophages are pivotal in control over solid tumors. Here the authors show that these macrophages express chemosensors that detect lipid variants in the tumor Read More
Site Logo
Powered by AI
New Journal Citation Reports (JCR) 2025
All-Time Views
1 Million+ Views and Counting..!
Follow me on Linkedin for Latest Jobs and Scholarships
Subscribe Youtube
Celebrating 6 Years
Now, it has been 6 years since it was launched in late July 2018 and is moving forward. Appreciate all the respected visitors! Please share this site with your friends to push science forward and improve human health.
Site Trust Score
Google Safe
Site Traffic
