The endogenous T cell landscape is reshaped by CAR-T cell therapy and predicts treatment response in multiple myeloma Summary CAR-T cell therapy for multiple myeloma significantly alters the patient’s existing T cell population. This Read More
Tags :Hematology
ICANS and mortality after CAR-T therapy for NHL patients can be predicted using physical function measures of falls, balance and strength deficits, and use of an assistive device Summary Physical function assessments can predict mortality Read More
Education, Research & Positions
Downregulation of MICA/MICB improves cell persistence and clinical activity of
Downregulation of MICA/MICB improves cell persistence and clinical activity of NKG2DL CAR T-cells in patients with relapsed or refractory acute myeloid leukemia or myelodysplastic neoplasia Summary CAR T-cell therapy targeting NKG2D ligands (Read More
Education, Research & Positions
Plasmapheresis facilitates soluble BCMA clearance and contributes to reversing primary
Plasmapheresis facilitates soluble BCMA clearance and contributes to reversing primary resistance to anti-BCMA immunotherapy in multiple myeloma Summary Plasmapheresis, a procedure that filters blood, has shown promise in overcoming resistance to anti-BCMA immunotherapies for multiple Read More
The impact of social determinants of health on outcomes of brexucabtagene autoleucel in adults with relapsed/refractory B-cell acute lymphoblastic leukemia Summary Social determinants of health (SDOH) significantly impact outcomes in adults with relapsed/refractory Read More
Safety and efficacy of autologous humanized CD19 CAR-T cell therapy for relapsed/refractory B-cell non-Hodgkin lymphoma Summary Autologous CD19 CAR-T cell therapy shows promise for treating relapsed/refractory B-cell non-Hodgkin lymphoma (r/r B-NHL). Studies Read More
Education, Research & Positions
Post-transplantation cyclophosphamide and antithymocyte globulin in 8/10 HLA-mismatched unrelated donor
Post-transplantation cyclophosphamide and antithymocyte globulin in 8/10 HLA-mismatched unrelated donor transplantation: the analysis on behalf of the transplant complications working party of the EBMT Summary A study by the EBMT’s Transplant Complications Working Party analyzed Read More
Education, Research & Positions
Impact of daratumumab refractoriness on clinical outcomes following CAR T-cell
Impact of daratumumab refractoriness on clinical outcomes following CAR T-cell therapy for relapsed refractory multiple myeloma Summary Daratumumab refractoriness significantly worsens outcomes after CAR T-cell therapy in patients with relapsed/refractory multiple myeloma. Studies show Read More
Education, Research & Positions
GPRC5D Bispecific antibody talquetamab-induced dizziness-ataxia syndrome, clinical presentation and management-
GPRC5D Bispecific antibody talquetamab-induced dizziness-ataxia syndrome, clinical presentation and management- a case series Summary This case series highlights a newly recognized side effect of talquetamab, a GPRC5D-targeting bispecific antibody used to treat multiple Read More
A novel chimeric antigen receptor T-cell therapy targeting CD84 for the treatment of acute myeloid and T-cell lymphoblastic leukemias Summary A novel CAR-T cell therapy targeting CD84 is showing promise for treating acute myeloid leukemia (Read More
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