The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as “gene scissors,” which enables researchers to better understand how human cells function and stay healthy. Researchers at Read More
Tags :functions
Scientists Discover Unique Functions of Specialized Immune Cells – New
The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. Summary The immune system defends the body against pathogens using Read More
TCF19 drives a broad transcriptional program that potentiates optimal innate
Nature Immunology, Published online: 08 August 2025; doi:10.1038/s41590-025-02238-z Sun and colleagues report that the transcription factor TCF19 regulates calcium signaling and cell cycling progression in NK cells and is required for innate and Read More
A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions
A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade Summary This research presents a novel CD27 agonistic antibody engineered for enhanced activity. By promoting hexamerization (Read More