Nature Immunology, Published online: 20 August 2025; doi:10.1038/s41590-025-02264-x Editorial Expression of Concern: Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR Summary Nature Immunology Read More
Science, Volume 389, Issue 6761, Page 711-715, August 2025. Summary Without specific details about the articles in that issue, a general summary is the best I can provide. Science, Volume 389, Issue 6761 (August 2025) likely presents cutting-edge research and commentary Read More
Investigating the correlation between IDO1/PD-L1 expression or co-expression and EGFR/KRAS gene mutations in advanced NSCLC Summary This study explores the relationship between IDO1 and PD-L1 expression (both individually and together) and the presence Read More
IC2Bert: masked gene expression pretraining and supervised fine tuning for robust immune checkpoint blockade (ICB) response prediction Summary IC2Bert proposes a novel deep learning framework for predicting patient response to Immune Checkpoint Blockade (Read More
MARCO expression on myeloid-derived suppressor cells is essential for their differentiation and immunosuppression Summary Myeloid-derived suppressor cells (MDSCs) require MARCO expression to properly differentiate and exert their immunosuppressive functions. MARCO, a scavenger receptor, plays a Read More
Intratumoral expression of IL-12 and CD40 ligand (CD154) from plasmids generates antitumor responses that eliminate tumoral T regs Summary Delivering plasmids encoding IL-12 and CD40L (CD154) directly into tumors can effectively trigger antitumor immunity. Read More
Science, Volume 389, Issue 6755, Page 31-32, July 2025. Summary Without specific article titles from the referenced Science issue, a precise summary is impossible. However, based on the general nature of Science and the page numbers given, this Read More
Science, Volume 389, Issue 6755, July 2025. Summary Without knowing the specific articles within that issue of Science, it’s impossible to provide a detailed summary. However, a general summary would be: Science, Volume 389, Issue 6755, published in July 2025, Read More
Abstract The prototypic IFN-inducible transcription factor, IRF1, not only controls inflammatory gene expression but also regulates T cell and macrophage fate specification and function. Using bone marrow chimeras (80% B6.129S2-Ighmtm1Cgn/J [µMT] + 20% B6.129Read More
Abstract Defining the MHC class I ligands of rhesus macaque killer cell Ig-like receptors (KIRs) is fundamental to NK cell biology in this species as a model for infectious diseases and comparative immunogenetics. Several rhesus Read More
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