Katie Burns is helping reveal the immune system’s role in the long-neglected disease Summary Katie Burns is pioneering research into mastocytosis, a rare disease where mast cells accumulate abnormally, causing diverse symptoms. She’s Read More
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Global study identifies upswing in photosynthesis driven by land, offset
Terrestrial plants drove an increase in global photosynthesis between 2003 and 2021, a trend partially offset by a weak decline in photosynthesis—the process of using sunlight to make food—among marine algae, according to a study Read More
Metabolic alterations driven by LDHA in CD8 + T cells promote immune
Metabolic alterations driven by LDHA in CD8 + T cells promote immune evasion and therapy resistance in NSCLC Summary Lung cancer cells often evade the immune system by manipulating CD8+ T cells, the body’s primary Read More
Nature Reviews Immunology, Published online: 30 June 2025; doi:10.1038/s41577-025-01205-x Maternal obesity during pregnancy promotes a form of fatty liver disease in offspring that is dependent on HIF1α-mediated rewiring of Kupffer cell metabolism. Read More
Resistance to anti-PD-1 therapy is driven by CD30+ regulatory T cell activity Summary Resistance to anti-PD-1 immunotherapy, a common cancer treatment, is often linked to the suppressive activity of CD30-expressing regulatory T cells (Tregs). Read More