Nature Immunology, Published online: 09 September 2025; doi:10.1038/s41590-025-02258-9 Dalit, Tan and colleagues provide a multiomic profile of T follicular helper (TFH) cells responses to diverse pathogens, revealing a blueprint for transcriptional flexibility and Read More
Nature Immunology, Published online: 22 August 2025; doi:10.1038/s41590-025-02247-y Using in vivo CRISPR–Cas9 screens of CD8+ T cells in a melanoma model, we identified STUB1 as an inhibitor of T cell-mediated antitumor immunity. Read More
Expanding the cytokine receptor alphabet reprograms T cells into diverse states Summary T cells, traditionally defined by a limited set of cytokine receptors, can be drastically reprogrammed by expanding this “receptor alphabet.” Research demonstrates that Read More
ICANS risk model in CD19 CAR-T therapy: insights from serum and CSF cytokine profiling Summary This study explores the predictive power of the Immune Cell-Associated Neurotoxicity Syndrome (ICANS) risk model in CD19 CAR-T therapy patients Read More
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