Some might say it looks like a finger. Others might see a worm. Scientists in the field often liken it to an antenna. The technical name is primary cilium. This slender, microscopic appendage juts out Read More
Tags :Cells
Nature Immunology, Published online: 29 August 2025; doi:10.1038/s41590-025-02255-y Alatrakchi and colleagues profile immune cells from liver and blood obtained from patients with MASLD/MASH using single-cell sequencing. They note increased immunoregulatory programs that Read More
GD2TIF cells as a platform for single-dose and long-term delivery of biologics Summary GD2TIF cells, genetically engineered to express therapeutic molecules in response to tumor-specific GD2 disialoganglioside, hold promise for single-dose, long-term biologic Read More
The vagus nerve is a critical structure, and cells it contains could help explain why flu infections can vary widely in patients Summary The vagus nerve, a major nerve connecting the brain to the body, Read More
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Collection of Immune Cells Drive Rheumatoid Arthritis Progression – New
Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints. Specifically, the immune system is attacking the body’s own tissue Summary Rheumatoid arthritis (RA) is a chronic autoimmune disease where the Read More
Education, Research & Positions
TCR-engineered T cells targeting a shared β-catenin mutation eradicate solid
Nature Immunology, Published online: 27 August 2025; doi:10.1038/s41590-025-02252-1 TCR-T cells are T cells engineered to express a specific T cell receptor. Here the authors present a TCR-T cell that targets CTNNB1-S37F, Read More
Education, Research & Positions
Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles
Engineering TCR-preserved allogeneic CAR-T cells: leveraging cancer immune evasion principles to establish T-cell tolerance Summary Engineering allogeneic CAR-T cells that retain their T cell receptor (TCR) could overcome challenges of current CAR-T therapies. By understanding Read More
Education, Research & Positions
Directed evolution-based discovery of ligands for in vivo restimulation of
Directed evolution-based discovery of ligands for in vivo restimulation of chimeric antigen receptor T cells Summary Researchers have developed a directed evolution approach to discover ligands that can specifically restimulate chimeric antigen receptor (CAR) T Read More
With today’s advanced microscopes, scientists can capture videos of entire embryos developing in real time. But there’s a catch: turning those breathtaking images into clean, accurate trajectories of each cell’s journey as Read More
Researchers bank on stem cells to study developmental biology, understand oral cancer, regenerate organs, and save species on the brink of extinction. Summary Stem cell research holds immense promise across diverse fields. Scientists are Read More
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