T cells engineered to target a shared β-catenin mutation eradicate solid tumors in mice Summary Genetically engineered T cells targeting a specific mutation in the β-catenin protein have shown remarkable success in eradicating solid tumors Read More
Tags :Cells
Education, Research & Positions
Publisher Correction: GD2-targeting CAR T cells in high-risk neuroblastoma: a
Publisher Correction: GD2-targeting CAR T cells in high-risk neuroblastoma: a phase 1/2 trial Summary A phase 1/2 clinical trial investigated the safety and efficacy of GD2-targeting CAR T cells in children and young adults with Read More
CD160+CD8+ T cells for improved immunotherapy Summary CD160+CD8+ T cells are a subset of cytotoxic T lymphocytes (CTLs) with enhanced antitumor activity. CD160, an activating receptor, distinguishes these cells and contributes to their Read More
Education, Research & Positions
Perovskite-Silicon Tandem Solar Cells Achieve Record-Breaking 33.1% Efficiency – New
Researchers have unlocked a new method of passivating perovskite-silicon tandem solar cells, achieving record efficiencies and laying the groundwork for more powerful solar technology. A group of international photovoltaics researchers has made an important advance Read More
Nature Reviews Immunology, Published online: 08 September 2025; doi:10.1038/s41577-025-01219-5 Functional and metabolic properties of innate-like T cells — namely, iNKT cells, MAIT cells and some γδ T cells — differ from those of conventional T cells. Read More
Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer Summary Engineering natural killer (NK) cells with chimeric antigen receptors (CARs) targeting tumor-associated antigens Read More
Education, Research & Positions
Publisher Correction: TNF and type I interferon crosstalk controls the
Nature Immunology, Published online: 05 September 2025; doi:10.1038/s41590-025-02293-6 Publisher Correction: TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells Summary The Nature Immunology paper, originally published online Read More
Researchers modified a protein in the cell elimination pathway to create a targeted system for destroying disease-causing cells, called Crunch. Summary Researchers engineered a new targeted cell-killing system called “Crunch” by modifying a protein involved Read More
Cells exposed to a month of extraterrestrial conditions accumulated molecular changes associated with aging and mutations linked to cancer. Summary Simulating a month of extraterrestrial conditions on human cells induced significant molecular alterations. Research revealed Read More
Education, Research & Positions
Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for
Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for targeting AXL in malignant peripheral nerve sheath tumors associated with NF1 Summary This research investigates the potential of CAR-T cell therapy to treat malignant peripheral nerve Read More
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