Scientists have uncovered how rogue DNA rings may help spark glioblastoma at its earliest stages. An international research team has shown that rogue rings of DNA that exist outside chromosomes, called extrachromosomal DNA, or ecDNA, Read More
Tags :cancers
Paul Mischel and others are testing therapies for rogue genetic loops that drive tumor evolution and growth Summary Paul Mischel and colleagues are pioneering new cancer therapies targeting rogue “extrachromosomal DNA” (ecDNA) loops. These loops, Read More
Triple-negative breast cancer cells build bridges to activate adipocytes and fuel themselves, highlighting a target for future therapies. Summary Triple-negative breast cancer (TNBC) cells, known for their aggressive nature, create physical connections, or “bridges,” to Read More
Education, Research & Positions
Advanced Ovarian and Endometrial Cancers Respond to Combination Immunotherapy –
Gynecological clear cell cancers (CCCs), very aggressive forms of ovarian and endometrial malignancies, respond poorly to chemotherapy. The low respo Summary Gynecological clear cell cancers (CCCs) are aggressive cancers of the ovary and endometrium Read More
Education, Research & Positions
This Common Anti-Nausea Pill Could Be a Game-Changer for Hard-To-Treat
An anti-nausea drug may reduce recurrence and death in aggressive breast cancer. Scientists are exploring its broader use in oncology. A recent study has identified a link between a widely used anti-nausea drug and improved Read More
Education, Research & Positions
Therapeutic targeting of mismatch repair-deficient cancers – New Study
Therapeutic targeting of mismatch repair-deficient cancers Summary Mismatch repair deficient (dMMR) cancers, characterized by high microsatellite instability (MSI-H), represent a distinct subset with unique vulnerabilities. Lacking proper DNA repair mechanisms, they accumulate mutations, leading to Read More
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