Publisher Correction: GD2-targeting CAR T cells in high-risk neuroblastoma: a phase 1/2 trial Summary A phase 1/2 clinical trial investigated the safety and efficacy of GD2-targeting CAR T cells in children and young adults with Read More
CD160+CD8+ T cells for improved immunotherapy Summary CD160+CD8+ T cells are a subset of cytotoxic T lymphocytes (CTLs) with enhanced antitumor activity. CD160, an activating receptor, distinguishes these cells and contributes to their Read More
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer Summary CD160, a surface receptor on CD8+ T cells, plays a crucial role in resistance to anti-PD-1 immunotherapy in colorectal cancer (Read More
Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against non-small cell lung cancer Summary Engineering natural killer (NK) cells with chimeric antigen receptors (CARs) targeting tumor-associated antigens Read More
Efficacy and safety of induction immunotherapy plus chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a meta-analysis Summary This meta-analysis investigates the efficacy and safety of adding induction immunotherapy to chemotherapy for locoregionally advanced nasopharyngeal Read More
Nature Immunology, Published online: 05 September 2025; doi:10.1038/s41590-025-02269-6 The pre-T cell receptor is essential for T cell development. It is also an emerging immunotherapy target. Summary The pre-T cell receptor (pre-TCR) is crucial Read More
Targeting necrotic lipid release in tumors enhances immunosurveillance and cancer immunotherapy of glioblastoma Summary Glioblastoma, a deadly brain cancer, often evades immune responses. This research explores a new strategy to boost immunosurveillance by targeting necrotic Read More
Evaluating CAR-T cells from neurofibromatosis type 1 (NF1) patients for targeting AXL in malignant peripheral nerve sheath tumors associated with NF1 Summary This research investigates the potential of CAR-T cell therapy to treat malignant peripheral nerve Read More
Supercharged NK cells: a unique population of NK cells capable of differentiating stem cells and lysis of MHC class I high differentiated tumors Summary A unique population of natural killer (NK) cells, termed “supercharged NK Read More
Simultaneous STING and lymphotoxin-β receptor activation induces B cell responses in tertiary lymphoid structures to potentiate antitumor immunity Summary Activating both the STING and lymphotoxin-β receptor (LTβR) pathways concurrently enhances B cell-mediated antitumor immunity. Read More
1 Million+ Views and Counting..!
It has been 7 years since it was launched in late July 2018, and it is moving forward. Appreciate all the respected visitors! Please share this site with your friends to push science forward and improve human health.
