Triple-negative breast cancer cells build bridges to activate adipocytes and fuel themselves, highlighting a target for future therapies. Summary Triple-negative breast cancer (TNBC) cells, known for their aggressive nature, create physical connections, or “bridges,” to Read More
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Science, Volume 389, Issue 6761, August 2025. Summary Without knowing the specific articles and content within the cited issue of Science, a precise summary is impossible. However, a general summary based on the journal’s typical scope would Read More
Empowering hypoxia to convert cold tumors into hot tumors for breast cancer immunotherapy Summary Recent research explores harnessing hypoxia, a common characteristic of “cold” tumors (those resistant to immunotherapy), to enhance breast cancer immunotherapy. By Read More
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CARG-2020 targets IL-12, IL-17, and PD-L1 pathways to effectively treat
CARG-2020 targets IL-12, IL-17, and PD-L1 pathways to effectively treat melanoma and breast cancer Summary CARG-2020 is a novel therapeutic strategy designed to treat melanoma and breast cancer by simultaneously targeting three crucial pathways involved Read More
Education, Research & Positions
This Common Anti-Nausea Pill Could Be a Game-Changer for Hard-To-Treat
An anti-nausea drug may reduce recurrence and death in aggressive breast cancer. Scientists are exploring its broader use in oncology. A recent study has identified a link between a widely used anti-nausea drug and improved Read More
Nature Immunology, Published online: 29 July 2025; doi:10.1038/s41590-025-02221-8 During late gestation, unconventional intraepithelial αβ T cells migrate from the gut to the mammary gland to remodel the tissue for lactation and enhance its mucosal Read More
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The untapped potential of radiation and immunotherapy for hormone receptor-positive
The untapped potential of radiation and immunotherapy for hormone receptor-positive breast cancer Summary Hormone receptor-positive (HR+) breast cancer, while treatable, often develops resistance to endocrine therapy. Emerging research explores combining radiation therapy with immunotherapy to Read More
Education, Research & Positions
New Discovery Provides Insight into Breast Cancer Response to Immunotherapy
According to the American Cancer Society, breast cancer is the most common cancer in women in the United States. Every 1 in 3 females are diagnosed with ov Summary I am sorry, I cannot summarize the provided Read More
Education, Research & Positions
Mobilizing antigen-presenting mast cells in anti-PD-1-refractory triple-negative breast cancer: a
Mobilizing antigen-presenting mast cells in anti-PD-1-refractory triple-negative breast cancer: a phase 2 trial Summary This phase 2 trial explores a novel approach to overcome resistance to anti-PD-1 immunotherapy in triple-negative breast cancer (TNBC). Researchers aim to Read More
A phase Ib/II trial of atezolizumab with cobimetinib or idasanutlin in metastatic estrogen receptor positive breast cancer Summary This phase Ib/II trial investigated the efficacy and safety of atezolizumab (an immunotherapy drug) combined Read More
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