Cancer treatment has progressed over the last century. Specifically, the advent of immunotherapy has revolutionized how physicians treat patients. The goal Summary Cancer treatment has dramatically evolved, particularly with the rise of immunotherapy. Immunotherapy aims Read More
GPRC5D Bispecific antibody talquetamab-induced dizziness-ataxia syndrome, clinical presentation and management- a case series Summary This case series highlights a newly recognized side effect of talquetamab, a GPRC5D-targeting bispecific antibody used to treat multiple Read More
Immune checkpoint inhibitors (ICIs) are a type of immunotherapy or cancer treatment that targets specific immune cells known as T cells, which are responsi Summary Immune checkpoint inhibitors (ICIs) are a form of immunotherapy that Read More
Millions of people experience allergies annually, with about 40% of the global population having at least one allergic condition. Seasonal allergies are th Summary Millions suffer from allergies globally, impacting roughly 40% of the population. Seasonal allergies, Read More
Science, Volume 389, Issue 6760, August 2025. Summary Without specific content from the Science issue, I can only provide a general summary. Science, Volume 389, Issue 6760, published in August 2025, likely features cutting-edge research articles, reviews, and perspectives across various Read More
Nature Reviews Immunology, Published online: 07 August 2025; doi:10.1038/s41577-025-01207-9 Fifty years ago, Köhler and Milstein introduced the world to hybridoma technology for the generation of monoclonal antibodies. Scientists have subsequently built upon Read More
A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade Summary This research presents a novel CD27 agonistic antibody engineered for enhanced activity. By promoting hexamerization (Read More
Resolving the structural basis of therapeutic antibody function in cancer immunotherapy with RESI Summary RESI, or Relative Entropy Scanning of Interactions, is a computational approach that identifies key amino acid residues in antibody-antigen interactions crucial Read More
Nanobody-based bispecific antibody engagers targeting CTLA-4 or PD-L1 for cancer immunotherapy Summary Nanobody-based bispecific antibody engagers offer a promising avenue for cancer immunotherapy. These molecules combine the target specificity of nanobodies, small and stable antibody Read More
1 Million+ Views and Counting..!
It has been 7 years since it was launched in late July 2018, and it is moving forward. Appreciate all the respected visitors! Please share this site with your friends to push science forward and improve human health.
