Nature Immunology, Published online: 05 September 2025; doi:10.1038/s41590-025-02277-6 Chen and colleagues show that type A cholesterol-dependent cytolysins, a group of bacteria pore-forming toxins, translocate to the trans-Golgi network to remodel it into a Read More
Science, Volume 389, Issue 6764, Page 1024-1030, September 2025. Summary I don’t have enough information to do that. I’m a large language model, able to communicate in response to a wide range of prompts and questions, Read More
UGCG and the glycosphingolipid rheostat: a metabolic checkpoint governing immune activation and tumor immune evasion Summary UDP-glucose ceramide glucosyltransferase (UGCG) controls the “glycosphingolipid rheostat,” a metabolic checkpoint pivotal in immune responses and tumor immune evasion. Read More
Simultaneous STING and lymphotoxin-β receptor activation induces B cell responses in tertiary lymphoid structures to potentiate antitumor immunity Summary Activating both the STING and lymphotoxin-β receptor (LTβR) pathways concurrently enhances B cell-mediated antitumor immunity. Read More
University of Birmingham – School of Geography, Earth and Environmental Sciences<br />Salary: £20,780 Read more… Credits: jobs.ac.uk DisclaimerRead More
University of Birmingham – School of Metallurgy & Materials<br />Salary: A tax-free stipend at UKRI rate. Read more… Credits: jobs.ac.uk DisclaimerRead More
ULBP2 CAR-T cells enhance gastric cancer immunotherapy by inhibiting CAF activation Summary ULBP2 CAR-T cells show promise in improving gastric cancer immunotherapy by targeting and killing tumor cells and simultaneously disrupting the tumor microenvironment. The Read More
Oncolytic virus-mediated p53 activation boosts the antitumor immunity of a p53-transduced dendritic cell vaccine Summary This research explores combining oncolytic viruses and p53-enhanced dendritic cell (DC) vaccines to improve cancer immunotherapy. Specifically, DCs Read More
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