Bioengineered immunocompetent preclinical trial-on-chip tool enables screening of CAR T cell therapy for leukaemia



Summary

Researchers have developed a bioengineered “trial-on-chip” system that mimics the human immune system to test CAR T-cell therapy effectiveness against leukemia. This microfluidic device integrates leukemia cells, immune cells, and a functionalized matrix to create a more realistic preclinical environment than traditional methods. The system accurately predicts CAR T-cell efficacy, offering a more efficient and cost-effective way to screen and optimize CAR T-cell therapies before human trials. This technology promises to accelerate the development of more effective and personalized cancer treatments.

Read more…

This post is part of “Science/Immunology News”, Follow for more…!!!