Chimeric exosomes-derived immunomodulator restoring lymph nodes microenvironment for sensitizing TNBC immunotherapy



Summary

This research explores a novel approach to improve immunotherapy response in Triple-Negative Breast Cancer (TNBC) using chimeric exosomes. These engineered exosomes, derived from immune cells, are designed to modulate the tumor microenvironment within lymph nodes. By delivering specific immunomodulatory signals, they aim to restore a more favorable immune context, overcoming the immunosuppressive environment often found in TNBC. This restoration enhances the sensitivity of TNBC to immunotherapy by promoting immune cell infiltration and activation within lymph nodes, ultimately leading to a stronger anti-tumor response. This approach holds promise for boosting the efficacy of immunotherapy in treating this aggressive cancer.

Read more…

Credits: Source

This post is part of “Science/Immunology News”, Follow for more…!!!